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Do you use docetaxel interchangeably with paclitaxel in breast cancer?

Does the answer vary based on whether it is neo/adjuvant or metastatic setting?
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What do you consider a reasonable taxane choice in the (neo)adjuvant setting?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Mayo Clinic Rochester
Answered on

The nuanced answer would be attuned to receptors, disease status (e.g. non-metastatic vs metastatic) and schedule.

In the adjuvant setting, defining studies include E1199 (Sparano et al JCO 2015) and S0221(Budd et al JCO 2015).

  • The ECOG trial examined weekly paclitaxel vs weekly docetaxel vs q3wk pac...

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