Do you use elacestrant for all patients with metastatic ER+, HER2-, ESR1 mutated breast cancer regardless of duration of response to prior ET+CDK4/6i?
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In patients with metastatic ER+, HER2-, ESR1-mutated breast cancer, how would duration of prior ET+CDK4/6i response impact your use of elacestrant?
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2 Answers
Mednet Member
Medical Oncology · Cochise Oncology
Answered on
Use elacestrant on all patients with ESR1 mutation regardless of length of response
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Mednet MemberInvited Expert
Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
Answered on · Updated on
EMERALD study enrolled patients with ER-positive/HER2-negative advanced breast cancer who had one or two lines of endocrine therapy, required pretreatment with a CDK4/6i, and ≤ 1 chemotherapy in all comers (with or without detectable ESR1 mutations). ESR1 mutation was detected in less than half (47....
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