Mednet Logo

Do you use elacestrant for all patients with metastatic ER+, HER2-, ESR1 mutated breast cancer regardless of duration of response to prior ET+CDK4/6i?

Community PollStarted

In patients with metastatic ER+, HER2-, ESR1-mutated breast cancer, how would duration of prior ET+CDK4/6i response impact your use of elacestrant?

117 physicians have voted

Join Mednetto vote and see how they answered.

2 Answers
Mednet Member
Mednet Member
Medical Oncology · Cochise Oncology
Answered on

Use elacestrant on all patients with ESR1 mutation regardless of length of response

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
Answered on · Updated on

EMERALD study enrolled patients with ER-positive/HER2-negative advanced breast cancer who had one or two lines of endocrine therapy, required pretreatment with a CDK4/6i, and ≤ 1 chemotherapy in all comers (with or without detectable ESR1 mutations). ESR1 mutation was detected in less than half (47....

Join for free or sign in to see the full answer