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Do you use oral etoposide in combination with carboplatin for small cell lung cancer, in light of the national shortage of IV etoposide?

If so, what would be the regimen?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Indiana Univ Simon Cancer Center
Answered on

Our preferred treatment for extensive SCLC is a platinum compound + IV etoposide. However with the national shortage, and our preference to "save" IV etoposide for metastatic germ cell tumors, we would use a platinum compound + irinotecan which is equivalent albeit with more G.I. toxicity. Another e...

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