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Do you use the highest or most recent PSA for risk stratification for newly diagnosed prostate cancer?

For example, if 2 pre-biopsy PSAs are 23 and then 18, would you stratify as intermediate or high risk? If otherwise intermediate risk, would you treat with short or long-term ADT?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Washington University School of Medicine
Answered on

This happens on occasion and can be a dilemma. First, I would repeat the PSA and see if it is <20 or >20, and take that into account. I would also take into account the genomic score. This may help further clarify the patient's risk category. If the patient had a reason for the first elevated PSA li...

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