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Are there instances when you would use urea to treat SIADH in patients with cirrhosis?

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Would you use urea to treat hyponatremia in a patient with cirrhosis?

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2 Answers
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Nephrology · UCLA
Answered on

In SIADH, the administered urea is subsequently excreted in the urine, resulting in a urea osmotic diuresis. The osmotic diuresis results in the excretion of water in excess of sodium and potassium, thereby leading to an increase in the serum sodium concentration. In contrast, the increased ADH secr...

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Mednet Member
Mednet MemberInvited Expert
Nephrology · Rush Medical College
Answered on

HypoNa in cirrhosis is the hardest HypoNA to treat IMO. It is hypervolemic hypoNa but diuretics dont usually help enough as they reposed poorly,, often in HRS or risking HRS, Tolvaptan is contraindicated (Black box) (even though I think that is overkill, a few doses won't hurt, the liver issues with...

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