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Do you utilize ctDNA-based MRD testing after frontline chemotherapy for DLBCL?

Which patients, if any, do you screen with ctDNA-based assays? What management strategies do you discuss with patients who are MRD-positive?
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What assay do you utilize for MRD testing, if any, for patients with DLBCL?

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1 Answer
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Medical Oncology · Rutgers Cancer Institute of New Jersey
Answered on

I do not, as part of the standard of care, in part because of limitations of the ClonoSEQ assay in this setting, and in part because of a lack of clarity around how best to manage a positive. However, there are a number of sophisticated clinical trials exploring this question prospectively, with a f...

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