Does aspirin dose (81 mg vs 325 mg) matter for secondary stroke prevention?
Should some patients get 325 mg instead of 81mg at least for a certain amount of time, such as patients in the acute phase of ischemic stroke or patients with symptomatic intracranial atherosclerosis (SAMMPRIS trial)?
1 Answer
Mednet MemberInvited Expert
Neurology · HCA Houston Healthcare
Answered on
This topic has been debated extensively. There are two camps in this debate:
- Aspirin with a dose of 81 mg is adequate for platelet inhibition in the general population.
- Aspirin with a dose of 325 mg may be needed for individuals who weigh more (>70 kg) to achieve appropriate platelet inhibition.
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