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Does cytotoxic chemotherapy affect the yield of germline testing?

Should testing for germline mutations -- eg. saliva sample -- occur before or after the completion of chemotherapy - or the timing does not matter?
1 Answer
Mednet Member
Mednet Member
Medical Oncology · OHSU
Answered on

Chemotherapy does not typically affect the yield or accuracy of germline testing for genetic mutations. Germline testing analyzes a person's DNA from a blood sample or other tissue to identify inherited genetic variants. This type of testing focuses on the genetic information that is present in the ...

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