Does evidence support extending the duration of intravenous iron dextran (INFeD) infusion in pregnant patients?
Are there specific safety or efficacy benefits associated with prolonged infusion times in this population?
Answer from: at Community Practice
Low molecular weight iron dextran (Infed) is a terrific option for pregnant patients with iron deficiency. Data from Wong et al., PMID 26971581 support the safety and efficacy of Infed in this patient population. Although the authors used a rapid infusion (1,000 mg in 1 hour), I tend to give Infed o...
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Answer from: Medical Oncologist at Academic Institution
No, there has never been evidence with any of the four formulations supporting a longer rate of infusion (above the minimum recommended) as a harbinger of either benefit or safety. LMW ID (INFeD) should be given as 1000 mg in 250 ml of normal saline over one hour. My gut tells me 45 minutes is OK bu...