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Does growth hormone (GH) replacement therapy reduce the risk of fractures in patients with GH deficiency?

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Mednet Member
Mednet Member
Endocrinology · Johns Hopkins Endocrinology and Pituitary Center

While long-term GH replacement in GHD individuals increased BMD (after an initial decline at 6 months point), I am not aware of any placebo-controlled study that convincingly showed an effect on fractures.

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Does growth hormone (GH) replacement therapy reduce the risk of fractures in patients with GH deficiency? | Mednet