Mednet Logo
CommunityRheumatology

Does hepatitis B vaccination reduce the risk of HBV reactivation associated with immunosuppressive therapy?

For example, in patients who are HbSAg negative, anti-HBc positive and HbSAb negative, does vaccination reduce reactivation risk?
2 Answers
Mednet Member
Mednet MemberInvited Expert
Rheumatology · Cleveland Clinic
Answered on · Updated on

Hepatitis B reactivation is a critical concern when patients are undergoing immunosuppressive therapy, often described as 'deadly but preventable.' Screening for HBV is strongly advised before initiating biologic therapies, targeted synthetic therapies, or high-dose immunosuppression, including HBsA...

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Rheumatology · Cleveland Clinic
Answered on

Thanks for the question and we apologize that our answer reads somewhat ambiguously as the answer to that is NO we do not vaccinate isolated anti-HBcore patients- we reworded our 'answer' to this question which we believe is clearer.

Join for free or sign in to see the full answer