Does isolated del(5q) have the same prognostic implications for post-PV secondary myelofibrosis as it does in MDS?
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1 AnswersMednet Member
Medical Oncology · Massachusetts General Hospital
Karyotypic abnormalities are rare in PV and ET. Abnormalities in myelofibrosis (MF) that are associated with an inferior prognosis are: 20q-, 13q-, +9, chromosome 1 translocation/duplication, -Y or sex chromosome abnormality other than –Y. There are few reports of del5q in MPN in general and not eno...