Does non-urothelial histology impact your approach to chemoradiotherapy for muscle-invasive bladder cancer?
For example, do you prefer a certain dose/fractionation, dose escalation, or chemotherapy regimen for SCC or other non-urothelial histologies?
Answer from: Radiation Oncologist at Academic Institution
There is no randomized data available in this regard to guide us through non-urothelial histologies for MIBC. However, certain points that are worth considering in their management are:
For small cell or neuroendocrine tumors, cisplatin/etoposide or ifosfamide/doxorubicin-based systemic therapy i...