Does ongoing methimazole requirement post radioactive iodine ablation therapy for toxic multinodular goiter suggest failure of therapy and need for repeat treatment or higher dose of radioactive iodine?

Toxic multinodular goiter may require more than one treatment with radioactive iodine (RAI) in order to achieve euthyroidism.

In follow-up to RAI therapy, I recommend also looking at the free T4 and free T3 levels, as the TSH may take longer to return to normal. If the free hormone levels have impro...