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Does pre-chemotherapy extent of nodal involvement impact your decision to offer adjuvant radiation in cN1, ypN0 triple-negative breast cancer?
E.g., does the quantity of clinically involved nodes, the size of involved nodes, or the extent of ENE prior to neoadjuvant chemotherapy and mastectomy impact your radiation decision-making with ypN0 disease?
Answer from: Radiation Oncologist at Academic Institution
There are few data on this subject. The group at the Netherlands Cancer Institute in Amsterdam created what they called the "MARI" approach for such patients (Koolen et al., PMID 28524246). In brief, they performed an axillary ultrasound and marked the largest suspicious node with a radioactive seed...
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