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Does preoperative use of somatostatin receptor ligand improve remission rates after surgery for acromegaly?

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Does preoperative use of somatostatin receptor ligand improve remission rates after surgery for acromegaly?

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Endocrinology · Johns Hopkins Endocrinology and Pituitary Center
Answered on

This is still an open question. Two well-known papers (one from Norway and one from China) addressed this and suggested that a 4-6 month treatment increased the chance of surgical cure for GH-secreting macroadenomas, but both papers had methodological issues. I have done this occasionally for macros...

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