Does R-CHOP provide durable remission in low-risk pediatric Burkitt or Burkitt-like lymphoma?
2 Answers
Mednet MemberInvited Expert
Pediatric Hematology/Oncology · Medical City Children’s Hospital
Answered on
It depends on your definition of "low-risk". Historically, the FAB defined low risk as FAB Group A (resected Murphy stage 1 tumor and resected Murphy stage 2 abdominal primary). Gerard's paper in BJH in 2008 reported a 98% EFS with two cycles of COPAD (basically CHOP with fractionated cytoxan) and n...
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Mednet MemberInvited Expert
Pediatric Hematology/Oncology · University of Toronto
Answered on
I agree with Dr. @Dr. First Last — the answer hinges on the definition of low risk disease.
Our adult colleagues found that younger adults (up to 30 or maybe even older) with diffuse large B- cell lymphoma did fine on R- CHOP because the younger adult patients had pediatric-type DLBCL, unlike the old...
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