Does your evaluation of a young person with spontaneous upper extremity DVT vary as compared to lower extremity DVT?

The workup for a young adult with an upper extremity DVT differs for me in two ways:

1. Venous thoracic outlet syndrome must be suspected and a careful history of repetitive overhead movements must be obtained. Consulting your vascular surgery team in these cases to ensure the anatomy does not put the patient at risk of a recurrent clot (and that the patient has the anatomy optimized if needed) is essential.
2. I would be much more likely to obtain an inherited thrombophilia workup (protein C/S, anti...