Does your institution omit prophylactic cranial irradiation in high risk ALL patients greater than 3 years of age?

Topics: Radiation Oncology • Pediatric Oncology

Does the St. Jude's Experience (NEJM 2009, PMID: 19553647) provide sufficient justification for routine omission in high risk patients?

Answer from: Radiation Oncologist at Academic Institution

The general trend worldwide has been to continue to reduce the proportion of patients receiving preemptive CNS directed radiotherapy, although some groups still utilize cranial radiotherapy in the front line setting for small subsets of patients with CNS3 disease at diagnosis, T-cell immunophenotype...

Comments

Radiation Oncologist at Coborn Cancer Center
How would you treat an isolated CNS relapse?

Related Questions