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Jonathan Samuels, MD

It's great to read the varying perspectives from more than one colleague on the same topic and see where they diverge or converge in their opinions. Many of the topics are directly relevant to issues I face daily, so it has facilitated some quick literature review and helped me provide the best care possible for my patients.

Jonathan Samuels, MD

Rheumatology

NYU Langone Health

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Rheumatology

How are you sequencing therapy in RA after a first TNF inhibitor fails?

13 replies9 agreedRheumatology
Invited Expert

Mednet Expert

RheumatologyNYU Langone Health

If the failure looks like secondary loss of response I check drug levels and antibodies before switching class. For primary non-response I move out of the class early, usually to a JAK inhibitor or abatacept depending on comorbidity and CV risk...

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