For 5 fraction lung SBRT, is 11 Gy per fraction superior to 10 Gy per fraction?  

The BED10 for 50 Gy in 5 fractions is 100, which is significantly lower then the BED of the 54 Gy in 3 fractions regimen (151). Since the Kestin/Grills paper (PMID#24630539) showed better local control with a BED10>105, should we be pushing the dose to 55 Gy in a 5 fraction plan?



Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Academic Institution