Topics:
Genitourinary Cancers • Medical Oncology • Renal Cell Carcinoma • NCI-CCC Tumor Board Question • UCSF • NCI-CCC GU Tumor Board Question
For a patient on dialysis with metastatic clear cell renal cancer, what regimen would you use after front line immunotherapy?
Answer from: Medical Oncologist at Academic Institution
For patients with ESRD on dialysis, prior data showed that pharmacokinetics of VEGF-TKIs in subjects with severe renal impairment were similar to those with normal renal function (Khosravan et al. 2010, Chen et al, 2016, Nguyen et al, 2016). Also, other retrospective studies showed safety of VEGF-TK...
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