For a patient with a large pheochromocytoma, how would you evaluate for possible autonomous cortisol co-secretion prior to adrenalectomy to assess need for risk of glucocorticoid withdrawal postoperatively?

Although rare, glucocorticoids carry the risk of precipitating a pheo crisis.

Systemic corticosteroids may trigger phaeochromocytoma crisis. Reactions Weekly. 2021;1859(1):5. doi: 10.1007/s40278-021-97101-2. Epub 2021 Jun 12. PMCID: PMC8195728.

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For a patient with a large pheochromocytoma, how would you evaluate for possible autonomous cortisol co-secretion prior to adrenalectomy to assess need for risk of glucocorticoid withdrawal postoperatively?

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