For a patient with a rising PSA after prostatectomy with seminal vesicles being negative for disease at surgery, do you ever treat the prostate bed and seminal vesicle bed with different doses in an SIB plan?

Conclusion: The short answer is no, I do not utilize de-escalation to the SV bed, and I treat the entire operative bed to 64-66.6Gy.

Below is a rationale and some linked resources, if helpful:

A. Dose: The recently published RTOG 0534 allowed a range of doses (64.8Gy-70.2 Gy); however, since the ini...