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For a patient with clinically node positive pancreatic cancer, do you simply boost the involved nodes to full dose or treat additional adjacent nodal regions electively?

This is presuming non-SBRT treatment for a locally advanced unresectable PDAC, to be treated with concurrent Xeloda with conventional fractionation. Do you simply contour and treat gross disease in both the pancreas and adjacent nodes with an expansion, or do you electively radiation nodal basins along with gross nodal disease?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Mayo Clinic School of Medicine
Answered on

I would recommend including an elective target volume. In your boost/high dose volume, you can include the involved primary and involved nodes with margin. The elective volume may include regions at risk for occult nodal involvement and pathways of peri-neural spread. This would align with the NRG c...

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