For a patient with unresectable EGFR positive lung adenocarcinoma treated with chemoradiation and a single site of oligometastasis treated definitively, would you consider durvalumab as per PACIFIC study or EGFR-directed therapy?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · UCSD Moores Cancer Center
Answered on
Technically, this is metastatic disease so I would do osimertinib here. I would avoid antiPD1 in known EGFR in metastatic setting due to pneumonitis risk when you have to start the EGFRi eventually
Join for free or sign in to see the full answer