For a pediatric patient with B-ALL who requires surgery during maintenance, what therapy modifications do you recommend to allow for optimal healing and minimal treatment disruption?
For a pediatric patient with B-ALL who needs elective surgery during maintenance, what are potential treatment options during the month recommended for healing in which myelosuppression should be minimal?
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Do you hold mercaptopuirne and methotrexate in the perioperative period of surgery during maintenance therapy of B-ALL?
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1 Answer
Mednet MemberInvited Expert
Pediatric Hematology/Oncology · Emory University
Answered on
If the patient has a history of stable ANC and platelet count while on mercaptopurine and methotrexate, no change in treatment is necessary. For a patient with unpredictable fluctuations in ANC and platelet count while on mercaptopurine and methotrexate, I recommend stopping oral antimetabolites two...
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