For a pediatric patient with B-ALL who requires surgery during maintenance, what therapy modifications do you recommend to allow for optimal healing and minimal treatment disruption?

If the patient has a history of stable ANC and platelet count while on mercaptopurine and methotrexate, no change in treatment is necessary. For a patient with unpredictable fluctuations in ANC and platelet count while on mercaptopurine and methotrexate, I recommend stopping oral antimetabolites two...