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For a postmenopausal patient with a pT2N0 breast cancer s/p BCS+SNB who qualifies for MA20, how do you decide between RNI, high tangents, and standard whole breast RT?

How would you modify this based on endopredict or RT-PCR?
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For a postmenopausal patient receiving whole breast radiation for pT2N0 disease, would you ever consider RNI for those with high-risk features as defined in MA.20 (at least one of the following: grade 3, ER negative, LVSI)?

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1 Answer
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Radiation Oncology · Michigan Healthcare Professionals, PC
Answered on · Updated on

TL;DR: "This patient would have fit Z11 criteria - if they had positive nodes. Patients did very well with tangents/high tangents. For N0 patients that would have been otherwise eligible for Z11, I would treat with standard whole breast RT."

The absolute reduction in isolated LRR in MA.20 was 5% at ...

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