For AML patients, when do you stop antiinfective agents?

Our practice is typically to continue an anti-viral throughout induction/consolidation without stopping the agent. We typically utilize anti-bacterial and anti-fungal when the absolute neutrophil count (ANC) is under 500 and then stop them once the ANC recovers to above 500. Our preferred anti-fungal is posaconazole based on (Cornely et al., PMID 17251531) but the need for anti-fungal prophylaxis may depend somewhat on region (Chen et al., PMID 35289704).

For patients on venetoclax, the duration ...