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For breast cancer with occult primary, do you favor radiation therapy or mastectomy for local management?

At what point would you decide to forego local control managment (RT or mastectomy) in favor of chemotherapy alone?
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

The incidence of occult primary in the breast has gone down significantly in the era of MRI imaging. That being said, in this uncommon situation where MRI imaging is negative, we favor RT to the breast along with regional nodes and the literature shows low IBTR in these patients.

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