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For early-stage, HR+ Her2- breast cancers, when do you use OncotypeDx v. Mammaprint?

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Which genomic test do you prefer for early-stage, HR+ breast cancers?

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2 Answers
Mednet Member
Mednet Member
Medical Oncology · Indiana University School of Medicine
Answered on

The reason to use any multiparameter assay is to determine which patients need chemo and which don't. To say that another way - it is about the predictive ability, not the prognostic ability. Until very recently, Mammaprint only had prognostic data so I always used Oncotype. The MINDACT trial recent...

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Mednet Member
Mednet Member
Medical Oncology · Kettering Cancer Center
Answered on

@Dr. First Last, I heard a talk where the speaker, based on MINDACT trial data used Mammaprint for early stage node positive patients to select patients that WILL NOT benefit from chemo (sparing chemo for almost half of those women). Conversely, he used OncotypeDx for early stage node negative breas...

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