For esophageal cancer treated with primary chemoradiotherapy, with residual disease on 3 months PET, would you repeat a PET at 6 months?

It depends on what the doc and the patient will do with the information. If the patient received primary chemo rads because they were not a surgical candidate initially, they would not be a surgical candidate after treatment. Thus, if there is a recurrence, any subsequent treatment would be palliative. Palliative treatments are, by definition, embarked upon to palliate specific symptoms. If the non-surgical candidate is asymptomatic, there is really no compelling need to re-PET at six months.

T...