For intermediate risk prostate cancer do you recommend short-term complete androgen blockade or LHRH agonist alone?

This is a good question with little data specifically addressing it. Anthony D'Amico et al. did a retropsecitve study of this issue in a cohort of high-risk patients who were treated with IMRT+brachy and showed complete blockade was associated with better prostate cancer specific mortality (Red J, 2...

I also like to do the combined androgen ablation with RT to stay consistent with the majority of the randomized studies done. There is a subset analysis of Anthony D'Amico's 206 patient study in which PSA recurrence rates were analyzed according to whether combined androgen blockade was received (as...