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For locally advanced NSCLC, does endobronchial tumor debulking just prior to treatment influence your decision making regarding bronchial tissue constraints/expected toxicity?

If concurrent chemo with conventionally fractionated RT were not an option, would debulking impact your decisions regarding dose/fractionation for hypofractionated courses?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Quillen VA Medical Center
Answered on

Bulky, large endobronchial lesions both bleed and obstruct. The concern should be the length and depth of the tumor. If destruction of the trachea or bronchial tumor risks bleeding and B/P fistula, it may account for some of the hazards associated with “ultra-central” location. The endobronchial deb...

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