For locally recurrent NSCLC after surgical resection but with subcentimeter ipsilateral nodules of indeterminate etiology, would you consider local therapy such as chemoradiation +/- durvalumab?

Time to relapse influences the treatment modality. Presuming relapse occurs at least a year or more after the initial surgery, we typically triage and re-evaluate if surgical resection is feasible again for local recurrence after prior resection. Since these are subcentimeter and of indeterminate et...