For newly diagnosed ALK or EGFR + NSCLC with oligometastases to brain only and otherwise cN0-1 thoracic disease, would you offer targeted therapy alone or SRS to brain + concurrent chemoradiation/surgery to chest?
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1 Answers
Mednet Member
Medical Oncology · UCSD Moores Cancer Center
For asymptomatic patients with smaller lesions, I would offer initial osimerinib or alectinib and get MRI with SRS planning sequences at 1month. We would then SRS any non-responding lesions
