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For patients who are incidentally found to have pT1a invasive breast cancer on excision for presumed atypia/DCIS without a sentinel lymph node biopsy, will you irradiate without the SLNB being performed?

How does patient age, grade, histology (IDC vs. ILC), and ER status affect your recommendations?
3 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

Unless systemic treatment would change, I would not push for SNLN as the yield of SNLN for low volume IDC has to be weighed against the small but not insignificant risk of lymphedema and other side effects. When treating with whole breast, would include level 1 and 2 in RT field.

In the era of syste...

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Radiation Oncology · Rush University Medical Center
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All those factors you listed are important. Is this a microinvasive cancer (i.e., few cells up to 2 mm), triple negative or ER/PR positive, age higher or lower? No LVI? How big was the DCIS component? How high was the DCIS grade (presume that atypia/DCIS issue was lower grade)? If this is a tiny inv...

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Radiation Oncology · Beth Israel Deaconess Medical Center
Answered on · Updated on

Please see my comments on the 2024 San Antonio Breast Cancer Symposium in this forum in January 2025 and also in February 2025 for more information. In brief, the multidisciplinary breast group at my hospital agreed in November 2024 on a guideline for offering omission of SLNB to patients undergoing...

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