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For patients with definite UIP and MPO-ANCA-associated vasculitis limited to the lungs (without systemic manifestations), what is the role of immunosuppression?

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Do you generally recommend immunosuppression for patients with definite UIP and MPO-ANCA-associated vasculitis limited to the lungs without other systemic manifestations?

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1 Answer
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Pulmonology · National Jewish Health
Answered on

I think in these subjects (as opposed to UIP in RA), immune suppression would be my first agent. The data are limited; there is some suggestion on biopsy that they have significant inflammation (Arnold et al., PMID 38574743). I would start with immunosuppression and have a low threshold to add anti-...

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