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For patients with high risk prostate cancer, is there data to support prostatectomy, as opposed to upfront RT?

I ask this because I am seeing more and more patients who have had surgery despite presenting with high risk disease.
1 Answer
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Radiation Oncology · Varian Medical Systems/Allegheny health network
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In 2010, MSKCC published a study in JCO which suggested surgery was better than 81 Gy IMRT for high risk prostate cancer. The study had many limitations including selection bias of higher stage patients. in the RT group, there was only short term androgen ablation, lack of salvage or delayed salvage...

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