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For patients with kidney stone disease and chronic kidney disease, is there an eGFR threshold at which you no longer recommend pursing 24 hour urine stone risk studies?

2 Answers
Mednet MemberInvited Expert
Nephrology · Medical College of Wisconsin
Answered on

While I agree with Dr. @Dr. First Last's comments in general, though, I have encountered patients that newly presented for stone disease at late stages of CKD and even on dialysis. The critical consideration is whether there is evidence of ongoing stone formation/growth. We must be aware that a stone passage event may not reflect active stone growth. Most patients can have retained stones for many years without suffering a passage event, only to have a stone suddenly break loose and pass due to ...

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Mednet MemberInvited Expert
Nephrology · Mayo Clinic
Answered on

I do not think we have much hard data to guide us as to whether and when we should stop kidney stone follow-up in chronic kidney disease. It makes sense to me that has the eGFR drops, there will be less urinary solute to make stones. For example, I had a florid cystine stone former who stopped making stones altogether when his diabetic nephropathy hit stage 5 CKD.

My personal practice is to decrease the frequency of urinary mineral monitoring if my stone patients reach stage 4 chronic kidney dis...

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