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For patients with newly diagnosed brain metastases without a history of seizure activity, do you routinely start anti-seizure medication?

If so, how long do you continue medication and when do you discontinue? Does treatment with surgical resection versus radiation alone change your management?
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For patients with newly diagnosed brain metastases without a history of seizure activity, do you routinely start anti-seizure medication?

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1 Answer
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Neurology · Wake Forest School of Medicine
Answered on

This is a common clinical question that has been repeatedly explored in meta-analyses and clinical guidelines. Consistently, there's no evidence to support primary prophylaxis for seizures in patients with brain tumors including brain metastases. In summary, the data does not support the routine use...

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