For premenopausal patients with early stage HR+ breast cancer for whom you are recommending tamoxifen, how do you select patients for extended endocrine therapy?
Are there clinical scenarios in which 5 years of tamoxifen alone remains sufficient?
Answer from: Medical Oncologist at Community Practice
For women who remain premenopausal after 5 years of adjuvant tamoxifen, NCCN guidelines recommend "consider tamoxifen for an additional 5 years," or no further therapy.
I consider extended use in most of my patients who reach this point, as a combined analysis of the ATLAS and aTTom studies sh...
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