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For stroke patients with ablated paroxysmal atrial fibrillation without known recurrence and ICAD, would you recommend dual antiplatelet therapy or anticoagulation with or without an antiplatelet agent?

What is the duration of each treatment choice and which drug is preferred by either group? What else should we take into consideration when deciding on treatment?
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For stroke patients with ablated paroxysmal Atrial fibrillation without known recurrence and ICAD, what is your preferred antithrombotic therapy?

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3 Answers
Mednet Member
Mednet Member
Neurology · University of Colorado, Climate & Health Dept
Answered on

Ablation treats cardiopulmonary symptoms, but it has not been adequately tested against anticoagulation for AFib-related stroke. Anecdotally, at least once a month, I will see a patient with an acute embolic-appearing stroke after their cardiologist has stopped their anticoagulation because they wer...

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Mednet Member
Mednet MemberInvited Expert
Neurology · Vanderbilt University Medical Center
Answered on

I would use DAPT for three months after the stroke. I do not see evidence for either anticoagulation or protracted DAPT for ICAD.

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Mednet Member
Mednet MemberInvited Expert
Neurology · Harvard Medical School
Answered on

Currently, it is unclear when and if to stop anticoagulation for AFib patients who have undergone a successful ablation. They need to be free of recurrence for at least a year to consider stopping anticoagulation and then the question is, how do you know that AFib has not recurred?

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