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Given the 10-year outcomes of UK FAST-Forward presented at ESTRO, how have you expanded the use of ultra-hypofractionation in your practice?

Should all breast cancer patients receive 5 fractions of radiation, or are there still some who need three weeks of treatment? Any hint that real-world data differ from the trial, especially regarding cosmesis?
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How routinely are you offering ultra-hypofractionated WBI (26Gy/5fx) given the 10-year outcomes of UK FAST-Forward?

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1 Answer
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

We offer 5 fractions to all early-stage breast cancer patients. If technically suitable, the preferred option is APBI; otherwise, FAST-Forward 26 Gy in 5, ensuring dose homogeneity as specified in the protocol.

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