Has the recent large observational data suggesting that continuing metformin during hospitalization is associated with lower post-discharge mortality and hypoglycemia changed your approach to holding it on admission in stable, non-critically ill patients with T2DM?
1 Answers
Mednet Member
Hospital Medicine · VA Boston Healthcare System
I really like this paper, but I don't think it is plausible that a 5-day difference in receipt of metformin (the median length of stay was 5 days) could really affect 90-day mortality.
The study question is a good one because the evidence that metformin causes lactic acidosis is extremely limited. In...