Have the 10-year results from UK FAST-Forward presented at ESTRO 2025 impacted your practice with regard to patient selection?   

I would consider our practice at Mayo as early adopters of ultra-hypofractionation for breast, largely driven by similar institutional trials for shorter courses and the patients we care for. As a result, we have pretty routinely offered 26 Gy/5 fraction whole breast RT since the 5-year follow-up wa...

For us, for most node negative patients, the standard is 5 fractions (APBI or whole breast based on technical or tumor factor); if they need boost after whole breast we use 10 Gy in 4 fractions. Have not done 5 fractions for those who need concurrent systemic treatment and use 40 in 15 with boost. ...