Have we established standard doses for radiation therapy for H&N cancers?
Are there dose-response studies establishing 70Gy is the optimal dose for gross tumor control, or is it simply thought to be the maximally tolerated dose?
Siimlarly, what publications/data support the doses we use for elective nodal coverage?
Are there scenarios where we can safely dose de-escalate off protocol?
1 Answer
Mednet Member
Radiation Oncology · Northeast Alabama Regional Medical Center
Answered on
You've asked a *really* wide-ranging, thought-provoking question. That said, if by 70 Gy you mean 35 fractions of 2 Gy apiece over 7 weeks as *the* "optimal dose," I can think of a few references off the top of my head where that's not optimal per se. Dosing also entails the timing/frequency of dose...
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