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What is your approach to using prazosin to treat day-time symptoms in PTSD?

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Mednet Member
Mednet Member
Psychiatry · Childrens Hospital Colorado

I will only use prazosin during the day if the patient is using it for sleep disturbance/nightmares. If they are not using prazosin, then I prefer guanfacine during the day.

If using prazosin, I start at 0.5 mg in the morning and then BID. I will titrate up based on reaction and side effects.

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