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Have you utilized silicone-based film-forming dressings to prevent, minimize, or treat radiation dermatitis?

Please share your patient selection criteria and experience. A recent study in H&N patients showed superiority of the StrataXRT gel over standard of care. What are your thoughts on this data?
1 Answer
Mednet Member
Radiation Oncology · Banner MD Anderson Cancer Center
Answered on

As the question author stated, Chan et al., PMID 31445838 from Queensland conducted an industry-funded single-blind randomized trial of StrataXRT (silicone-based barrier vs. Sorbolene) (glycerin-based emollient - standard arm) in 197 patients getting 50 Gy or more to the head and neck. They found a lower incidence of grade 2 (80% vs 91%) and grade 3 (28% vs. 45%) in those getting StrataXRT compared to standard of care Sorbolene which persisted in multivariate analysis.

Ahn et al., PMID 31882508 also found StrataXRT reduced dermatitis in breast cancer patients.

Note that in the US, it is considered a medical device and has variable insurance coverage and/or cost to the patient. ScarAway cream may offer the same benefit as well as other generi...

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